Position Snapshot

Location: Vers-chez-les-Blanc, Lausanne, Switzerland
Company: Nestlé Health Science
Permanent contract 
Full-time, Act. Rate 100%
PhD or PhD/MD. Scientific mastership in microbiome and associated effects on human health
Experience in early drug development is required 
 

Position Summary

Nestlé Health Science is a globally recognised leader in the science of nutrition, with more than 7,000 employees around the world. With a portfolio of science-based consumer health, medical nutrition, vitamin and supplement brands, and pharmaceutical therapies, we are redefining the management of health. 
Reporting to the Global Head of Translational Research, the Global Scientific Lead Microbiome Therapeutics is responsible to identify and develop Microbiome based therapeutic solutions in key strategic areas and initiate studies on behalf of NHSc with external partners or at Contract Research Organizations (CROs). In this role, you will also represent research, preclinical and early development in project teams to support the development of therapeutic microbiota derived clinical candidates. 
 

A day in the life of a Global Scientific Lead Microbiome Therapeutics (Rx)

•    Design and execute IND- and CTA- enabling in vivo non-clinical programs to advance key development programs, including preclinical/non-clinical study plan, timelines and budget Drive first in human/POC studies, working closely with regulatory and clinical development
•    Identify early to late-stage compounds in key areas and new indications with successful generation of IP
•    Identification of target engagement and mode of action, as well as scientific or clinical biomarkers and contribution to designing of clinical studies
•    Scientific evaluation of licensing opportunities 
•    Implementation of scientific discoveries and/or early-stage external assets in the therapeutic area associated I&R portfolio    
•    Coordinating external collaborations with international academic and industrial partners/biotech. Present and attend at scientific conferences
•    Review scientific and technical aspects of nonclinical studies performed with external collaborators or CROs
•    Review and finalize nonclinical study reports (both non-GLP and GLP studies)
•    Communicate with regulatory agencies to resolve non-clinical issues.             
•    Act as Preclinical Development representative on project teams and/or sub teams for the development of novel microbiome therapeutics (Rx)

What will make you successful

•    Ph.D. or MD/PhD in Biomedical Sciences (e.g. Biochemistry, Microbiology, Immunology) with specialization in microbiome research and early development.
•    Drug development experience, with minimum 3 to 5 years working in biotech/pharma companies
•    Experience in coordination, organization, analysis, and documentation of nonclinical studies 
•    Experience in Gastroenterology and Immunology related diseases